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Long-term outcomes of ventral hernia repair: Effect of patient, hernia, and technical characteristics on recurrence
Aymen H. Sadaka1,2, William J. O’Brien3, Kamal M.F. Itani1,2,4
1VA Boston Dept. of Surgery, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3VA Boston CHOIR, Boston, MA, 4Harvard Medical School, Boston, MA

Background: There is no consensus on the best ventral hernia repair (VHR). This study aims to determine which patient, hernia, and technical factors are associated with long-term recurrence.
Methods: Since 2011, the New England VA Hernia Registry (NEVAHR) prospectively collected operative details of VHRs from 5 VA medical centers. Records and imaging were reviewed from operation to March 2024 for recurrence, skin and soft tissue infections (SSTI), mesh infections, and surgical site occurrences (SSO – hematoma, seroma, wound dehiscence). Logistical regression of NEVAHR data, alongside patient characteristics from VASQIP, was used to determine the factors associated with recurrence.
Results: There were 681 VHRs, with a median follow-up of 7 years, consisting of 407 (49.8%) midline incisional, 182 (26.7%) epigastric, 38 (5.6%) lower quadrants, 26 (3.8%) subcostal, 16 (2.3%) parastomal, and 12 (1.8%) Spigelian hernias. Mesh was used in 589 (86.5%) repairs and was associated with larger average horizontal (5.8cm vs 2.5cm) and vertical (6.9cm vs 2.6cm) defect sizes (p<0.001). There were 117 (19.9%) recurrences among mesh repairs and 22 (23.9%) recurrences among suture repairs (p=0.033). Post-op complications, including 61 SSTIs and 111 SSOs, were associated with increased recurrences (p=0.008). Among mesh repairs, recurrence was associated with higher BMI (p=0.009), smoking history (p=0.012), biologic mesh (p=0.003), parastomal and subcostal hernias (p=0.003; p=0.042), post-op complications including 13 mesh infections (p=0.009), and laparoscopy (p=0.042). Among suture repairs, no factors were associated with recurrence.
Conclusion: Suture repair was associated with increased recurrence. Recurrence among mesh repairs was associated with BMI, smoking, hernia type, biologic mesh, post-op complications, and laparoscopy.
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